AQA | GCSE Biology | Paper 2 | 2025 Predictions

AQA GCSE Biology Paper 2 – 2025 Predictions Are Here! 🔬✨

Author

Jen - Primrose Kitten
March 05, 2025

Hey 👋

Get ready to smash your AQA GCSE Biology Paper 2 with our 2025 Predicted Papers! 🧪📚

Last year, we nearly predicted EVERY single topic correctly! 🔥🎯 And this year, we’ve analysed all the trends and patterns again to bring you:

✅ Exam-style questions designed to match the real thing 📝
✅ Mark schemes so you know exactly how to score top marks ✅
✅ NEW for 2025 🎥 FREE video walkthroughs showing you how to write answers the way examiners love! 🏆

Want even MORE support? 🎯 Join our Masterclasses to get:
🌟 Access to our Revision Accelerator Course over the school holidays 🚀
🌟 Live exam prep sessions the night before your exam for that final confidence boost! 🎧📢

We’ve done the hard work, but don’t forget—revise everything to be fully prepared! 💡💪

Ready to boost your grade? Grab your predicted papers & masterclass spot

You’ve got this! 🌟💖

Which paper are you looking for?

AQA | GCSE Separate Science Biology | Higher | Paper 2 | 2025 Predicted Topics & Revision Guide

Here are our 2025 predictions for AQA GCSE Biology Higher Paper 2! 🔬✨ These are the topics we think are most likely to come up—so make sure you know them inside out! 💪📚

🧠 Structure and Function of the Nervous System

✅ Role of the CNS (central nervous system) – brain & spinal cord
✅ Reflex arcs – how they work and why they’re important
✅ The structure of a neurone and the role of synapses (neurotransmitters!)

🧠 The Brain

✅ Key structures – cerebrum, cerebellum, medulla, hypothalamus, pituitary gland
✅ How scientists study the brain – brain damage, electrical stimulation, MRI scans
✅ Why the brain is hard to treat (delicate, complex, not fully understood!)

🩸 Blood Glucose Control and Diabetes

✅ Role of insulin & glucagon in maintaining blood sugar levels
✅ Type 1 vs. Type 2 diabetes – causes, symptoms, and treatments
✅ Negative feedback and the role of the pancreas

🧬 Genetic Inheritance

✅ Alleles, dominant vs. recessive, genotypes & phenotypes
✅ Punnett squares – how to predict inheritance probabilities
✅ Genetic disorders – cystic fibrosis and polydactyly

🌱 Sampling Techniques (RP9 – Quadrats & Transects)

✅ Quadrats & transects – how and why we use them
✅ Random vs. systematic sampling – avoiding bias
✅ Abiotic & biotic factors affecting population size

🦠 Decay Practical (RP10)

✅ Factors affecting decay – temperature, oxygen, water, microbes
✅ Investigating milk decay – role of lipase & pH indicator
✅ Applications – composting & sewage treatment

🐶 Selective Breeding

✅ Process – choosing parents, breeding over generations
✅ Uses – crops (higher yield), animals (disease resistance, meat/milk production), pets (temperament, appearance)
✅ Risks – inbreeding, reduced genetic variation, increased health issues

🦎 Variation and Adaptation

✅ Genetic vs. environmental variation – examples of each
✅ Adaptations to environment – structural, behavioural, physiological
✅ How variation links to natural selection

🧬 Cloning

✅ Types of cloning – tissue culture, cuttings, embryo transplants, adult cell cloning
✅ Pros & cons – biodiversity loss, ethical issues, medical uses
✅ Applications – agriculture, conservation, medicine

🌳 Classification

✅ Carl Linnaeus’ classification system – kingdom, phylum, class, order, etc.
✅ Binomial naming system – Genus + species
✅ Three-domain system (Bacteria, Archaea, Eukarya)

🦴 Fossils and the Theory of Evolution

✅ What fossils are & how they form
✅ Evidence for evolution from fossil records
✅ Why some fossils are missing – decay, destruction, or never forming

🧬 Advantages and Disadvantages of Sexual and Asexual Reproduction

✅ Sexual reproduction – genetic variation, disease resistance, slower
✅ Asexual reproduction – clones, rapid reproduction, good for stable environments
✅ Examples – bacteria (binary fission), plants (runners, bulbs), fungi (spores)

🌍 Global Warming

✅ Causes – CO₂, methane, human activities
✅ Effects – rising sea levels, habitat loss, extreme weather
✅ Solutions – renewable energy, conservation, reducing carbon footprint

🍽️ Food Security

✅ Factors affecting food supply – population growth, climate change, farming practices
✅ Strategies – sustainable farming, reducing waste, GM crops (higher yield, pest resistance)

🦠 Uses of Biotechnology – Novel Food Production (Not GM!)

✅ Mycoprotein (Quorn!) – made using fungi (Fusarium), grown in fermenters
✅ Single-cell protein (SCP) – using bacteria & algae for protein-rich foods
✅ Enzymes in food production – lactase for lactose-free milk

🔥 Final Advice!

📌 These topics are predicted, but the exam could include anything from the syllabus—so revise everything!
📌 Practise past papers & mark schemes to get used to the question styles!
📌 Need extra help? Join our Masterclasses for revision sessions and live exam prep the night before! 🎧📢

You’ve got this! 💪✨

AQA Trilogy | GCSE Combined Science Biology | Higher | Paper 2 | 2025 Predicted Topics & Revision Guide

Here are our 2025 predictions for AQA GCSE Combined Science Biology Higher Paper 2! 🔬✨ While we’ve carefully analysed trends, remember to revise everything to be fully prepared! 💡📚

⚡ Reflex Arc

✅ Automatic response – doesn’t involve the brain to keep reaction fast!
✅ Pathway: Stimulus → Receptor → Sensory neurone → Relay neurone → Motor neurone → Effector → Response
✅ Role of synapses – neurotransmitters pass the signal across gaps between neurones

🧬 Inheritance – Family Trees & Punnett Squares

✅ Dominant vs. recessive alleles – dominant only needs one copy to show
✅ How to use Punnett squares to predict genetic outcomes
✅ Family trees – spotting inherited traits & genetic disorders (e.g. polydactyly or cystic fibrosis)

🌱 Required Practical – Transect Sampling

✅ Quadrats & transects – used to measure how species are distributed in an area
✅ Abiotic factors (e.g. light, temperature, water) affect population sizes
✅ How to improve reliability: repeat, random sampling, control variables

🌿 Biotic and Abiotic Factors

✅ Biotic factors = living things affecting an ecosystem (e.g. predators, disease, food availability)
✅ Abiotic factors = non-living things affecting an ecosystem (e.g. temperature, pH, water levels)
✅ How changes in these factors affect population sizes and biodiversity

🌍 Global Warming

✅ Caused by greenhouse gases (carbon dioxide, methane) trapping heat
✅ Effects: rising sea levels, extreme weather, habitat destruction
✅ Solutions: renewable energy, reducing carbon footprint, planting trees

♻️ Waste Management

✅ Pollution types – land (landfills), water (plastics), air (smoke, acid rain)
✅ How human activity affects biodiversity (e.g. deforestation, habitat destruction)
✅ Ways to reduce waste – recycling, conservation, sustainable farming

🦋 Maintaining Biodiversity

✅ Why biodiversity is important – stable ecosystems, medicine, food chains
✅ How to conserve species – breeding programmes, habitat protection, reducing deforestation
✅ Role of governments & charities in conservation efforts

🐶 Selective Breeding

✅ Used to produce desirable traits (e.g. high-yield crops, disease-resistant animals)
✅ Risks – inbreeding (health problems), reduced variation, more disease susceptibility
✅ Ethical concerns – animal welfare, reduced gene pool

🦴 Classification, Fossils, and Evolution

✅ Classification – Linnaeus’ system (Kingdom, Phylum, Class…) & three-domain system (Bacteria, Archaea, Eukarya)
✅ Fossils – evidence for evolution, how they form, why some are missing
✅ Natural selection – survival of the fittest, how species evolve over time

🩸 Contraception and Menstrual Cycle Hormones

✅ Key hormones:

  • FSH – matures the egg

  • LH – releases the egg (ovulation)

  • Oestrogen & progesterone – control the cycle & maintain uterus lining
    ✅ Contraception types:

  • Hormonal (pill, implant, injection) – stop ovulation

  • Barrier (condoms, diaphragms) – prevent sperm reaching egg

  • Surgical (sterilisation) – permanent prevention

💡 Final Advice & Masterclasses!

🔥 These topics are predicted, but anything from the syllabus could appear—so revise widely!
🔥 Practice past papers and learn mark schemes to see how examiners award points!
🔥 Join our Masterclasses for extra support, revision boosters, and live exam prep sessions the night before! 🎧📢

💙 Most importantly, take care of yourself! Exam stress is real, but your grades do not define you! Take breaks, sleep well, and believe in yourself—you’ve got this! 💪✨

👉 Get your predicted papers & masterclass spot here

AQA | GCSE Separate Science Biology | Foundation | Paper 2 | 2025 Predicted Topics & Revision Guide

Here are our 2025 predictions for AQA GCSE Biology Foundation Paper 2! 🔬✨ These are key topics we think might come up, so make sure you’re confident with them! But remember—revise everything just in case! 💪📚

⚡ Reflex Arc

✅ A fast, automatic response to protect the body
✅ Pathway: Stimulus → Receptor → Sensory neurone → Relay neurone → Motor neurone → Effector → Response
✅ Reflexes help to avoid injury (e.g. pulling hand away from something hot)

🧠 The Brain

✅ Controls movement, memory, emotions, and bodily functions
✅ Key parts to know:

  • Cerebrum – thinking, memory, speech

  • Cerebellum – balance and coordination

  • Medulla – controls heartbeat and breathing
    ✅ Why brain damage is difficult to treat – delicate & complex!

🩸 Blood Glucose Control and Diabetes

✅ The pancreas controls blood sugar levels using two hormones:

  • Insulin – lowers blood sugar when it’s too high

  • Glucagon – raises blood sugar when it’s too low
    ✅ Diabetes:

  • Type 1 – body doesn’t produce insulin (needs injections)

  • Type 2 – linked to diet and lifestyle (managed with healthy eating & exercise)

🚽 Excretion

✅ The removal of waste products from the body
✅ The kidneys filter blood to remove urea, water, and salts (forming urine)
✅ The lungs remove carbon dioxide, and the skin removes sweat

🧬 Inheritance – Family Trees & Punnett Squares

✅ Dominant vs. recessive genes – dominant only needs one copy to show
✅ How to use a Punnett square to predict genetic traits
✅ Family trees help show how traits are passed through generations

🌱 Required Practical – Transect Sampling

✅ Quadrats & transects – used to measure plant and animal distribution
✅ Abiotic factors (e.g. light, temperature) affect where organisms live
✅ To make results reliable – repeat tests and take averages

🌿 Biotic and Abiotic Factors

✅ Biotic (living) factors: predators, food availability, disease
✅ Abiotic (non-living) factors: temperature, water, light, soil type
✅ Changes in these factors can increase or decrease population sizes

🌍 Global Warming

✅ Causes: too much carbon dioxide (CO₂) & methane in the atmosphere
✅ Effects: rising temperatures, melting ice, extreme weather
✅ Ways to reduce it: using less fossil fuels, planting more trees

🍽️ Food Security

✅ Challenges: growing population, climate change, overfishing
✅ Solutions:

  • Sustainable farming methods

  • Reducing food waste

  • Improving food transport & storage

🦠 Biotechnology

✅ Using microorganisms to help in food and medicine production
✅ Examples:

  • Mycoprotein (Quorn!) – made using fungi

  • Bacteria used to produce insulin for diabetes treatment

🐶 Selective Breeding

✅ Choosing parents with desired traits to breed together
✅ Used for:

  • Farming (cows that produce more milk)

  • Pets (dogs with good temperaments)

  • Crops (disease-resistant plants)
    ✅ Risks – inbreeding can cause health problems

🦴 Classification, Fossils, and Evolution

✅ Classification – grouping organisms based on similarities
✅ Fossils – evidence for evolution, show how species have changed over time
✅ Evolution – species gradually change to adapt to their environment

🧬 Theory of Evolution

✅ Charles Darwin’s theory – natural selection (survival of the fittest)
✅ Mutations cause variation, and beneficial traits get passed on
✅ Over time, this leads to new species forming

🧪 Cloning

✅ Types of cloning:

  • Cuttings & tissue culture (for plants)

  • Embryo transplants (for animals)

  • Adult cell cloning (e.g. Dolly the sheep)
    ✅ Benefits – conservation & farming
    ✅ Risks – ethical concerns, lack of genetic variation

🧬 Sexual and Asexual Reproduction

✅ Sexual reproduction – two parents, produces variation (important for evolution!)
✅ Asexual reproduction – one parent, identical offspring (good for quick reproduction)
✅ Examples:

  • Bacteria & fungi reproduce asexually

  • Plants can do both (e.g. runners in strawberries)

💡 Final Advice & Masterclasses!

🔥 These topics are predicted, but remember—revise everything!
🔥 Practise past papers to get used to the types of questions that come up
🔥 Need extra support? Join our Masterclasses! We’ve got revision boosters and live exam prep the night before to help you feel ready! 🎧📢

💙 Most importantly, look after yourself! Exam stress is normal, but your grades do not define your worth. Take breaks, eat well, and believe in yourself—you’ve got this! 💪✨

👉 Get your predicted papers & masterclass spot here

AQA Trilogy | GCSE Combined Science Biology | Foundation | Paper 2 | 2025 Predicted Topics & Revision Guide

Here are our 2025 predictions for AQA GCSE Combined Science Biology Foundation Paper 2! 🔬✨ These are key topics we think might come up, so make sure you’re confident with them! But remember—revise everything to be fully prepared! 💪📚

⚡ Reflex Arc

✅ A fast, automatic response to protect the body from harm
✅ Pathway: Stimulus → Receptor → Sensory neurone → Relay neurone → Motor neurone → Effector → Response
✅ Example: Pulling your hand away from something hot

🧬 Inheritance – Family Trees & Punnett Squares

✅ Genes are passed from parents to offspring
✅ Dominant vs. recessive traits – dominant only needs one copy to show
✅ How to use Punnett squares to predict how traits are inherited
✅ Family trees show how genetic conditions are passed down

🌱 Required Practical – Transect Sampling

✅ Quadrats & transects help measure how plants & animals are spread in an area
✅ Abiotic factors (e.g. temperature, light) affect where organisms live
✅ To improve accuracy – repeat tests and take averages

🌿 Biotic and Abiotic Factors

✅ Biotic factors (living things) – predators, food supply, disease
✅ Abiotic factors (non-living) – temperature, water, soil pH, light
✅ Changes in these factors can affect population sizes

🌍 Global Warming

✅ Causes: Too much carbon dioxide & methane from cars, factories, farming
✅ Effects: Rising sea levels, extreme weather, habitat destruction
✅ Ways to reduce it: Renewable energy, recycling, planting trees

♻️ Waste Management

✅ Types of pollution:

  • Land (litter, landfills)

  • Water (plastic in oceans)

  • Air (fumes, smoke, acid rain)
    ✅ Solutions: Recycling, reducing plastic use, better waste disposal

🦋 Maintaining Biodiversity

✅ Why it’s important: Keeps ecosystems stable, provides food & medicine
✅ Threats to biodiversity: Deforestation, climate change, pollution
✅ How to protect it: Nature reserves, reforestation, reducing waste

🐶 Selective Breeding

✅ Humans choose parents with desirable traits (e.g. faster-growing crops, high milk-yield cows)
✅ Used for: Farming, pets, disease-resistant plants
✅ Risks – inbreeding can cause health problems

🦴 Classification, Fossils, and Evolution

✅ Classification: Grouping organisms based on similarities (e.g. mammals, reptiles)
✅ Fossils: Show evidence of how species have changed over time
✅ Evolution: Natural selection – survival of the fittest leads to gradual changes in species

🩸 Contraception and Menstrual Cycle Hormones

✅ Key hormones:

  • FSH – matures the egg

  • LH – releases the egg (ovulation)

  • Oestrogen & progesterone – control the cycle & maintain uterus lining
    ✅ Contraception methods:

  • Hormonal (pill, implant, injection) – stops ovulation

  • Barrier (condoms, diaphragms) – stops sperm reaching the egg

  • Surgical (sterilisation) – permanent prevention

💡 Final Advice & Masterclasses!

🔥 These topics are predicted, but remember—revise everything!
🔥 Practise past papers to get used to the types of questions that come up!
🔥 Need extra support? Join our Masterclasses! We’ve got revision boosters and live exam prep sessions the night before to help you feel exam-ready! 🎧📢

💙 Most importantly, look after yourself! Exam stress is real, but your grades do not define your worth. Take breaks, eat well, and believe in yourself—you’ve got this! 💪✨

👉 Get your predicted papers & masterclass spot here